The Present Invention Relates To RNA Interference-Based Methods For Inhibiting The Expression Of The Myotilin Gene. Recombinant Adeno-Associated Viruses Of The Invention Deliver Dnas Encoding Micrornas That Knock Down The Expression Of Myotilin. The Methods Have Application In The Treatment Of Muscu...
The Invention Relates To Construction, Screening And Application Of GRP78 (Glucose Regulated Protein 78) Gene Targeted RNA Interference Recombinant Lentivirus Vectors. With Use Of An RNA Interference Technique, Aiming At Different Target Sequences Of A GRP78 Gene, Four Lentivirus Eukaryotic Expressi...
Disclosed Are Methods And Compositions For Inhibiting DNA Synthesis In A Cell Using RNA. Inhibition Of DNA Synthesis By RNA Can Be Used, For Example, In Analytical Methods, As A Research Tool To Affect Cells Under Study, To Synchronize Cell Cycle In A Cell Culture, And To Inhibit Cell Growth. For Ex...
The Invention Provides A Berberine Affinity Labeling Probe And A Preparation Method Thereof And Belongs To The Field Of Biological Detection. The Probe Comprises Four Functional Parts Including An Active Group, Namely, Berberine, An Affinity Labeling Group, A Connection Part And A Reporter Group. Af...
RNA Interference Is Provided For Inhibition Of Tumor Necrosis Factor Α (Tnfα) By Silencing Tnfα Cell Surface Receptor TNF Receptor-1 (TNFR1) Mrna Expression, Or By Silencing Tnfα Converting Enzyme (TACE/ADAM17) Mrna Expression. Silencing Such Tnfα Targets, In Particular, Is Useful For Treating ...
This Invention Is Directed To The Compositions And Methods For Inducing Female Gonad Maturation In Crustacean Species Such As Shrimp, Lobster Or Crab. In One Embodiment, The Composition For Inducing Gonad Maturation Comprises A Dsrna Corresponding To The GIH DNA, Recombinant Protein Of A Gonad Stimu...
The Present Invention Is Directed To Nucleic Acid Molecules Containing A Loop Sequence Designed To Circumvent Exportin-5 Mediated Export, And Methods Using These Novel Molecules.
Compositions And Methods For Treating Cardiomyopathy Using RNA Interference Are Disclosed. In Particular, Embodiments Of The Invention Relate To The Use Of Oligonucleotides For Treatment Of Cardiomyopathy, Including Small Interfering Rnas (Sirnas) And Short Hairpin Rnas (Shrnas) That Silence Express...
The Invention Relates To The Technical Field Of Biology, In Particular To A Human JNK1 (C-Jun N-Terminal Kinase) Gene Targeting Small Interfering RNA (Ribonucleic Acid) And Application Thereof. The Small Interfering RNA Comprises A Sense Strand And An Anti-Sense Strand, A Nucleotide Sequence Of The ...
The Invention Belongs To The Technical Field Of Plant Gene Engineering And Relates To A Ribonucleic Acid (RNA) Interference Vector Of A Cotton Fiber Specific Arabinogalactan Protein Glycosyl Transferase Ghgalt1 Gene, And A Construction Method And Application Thereof. The RNA Interference Vector Comp...
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